Born in Ashland, Kentucky, Alberta Vaughn was a selected as a WAMAPS Baby Star along with Clara Bow and Dorothy Mackaill in 1924. Her movie career began in 1921 and continued until 1935. She often co-starred with actor Al Cook in comedies. She made Randy Rides Again (1934) with John Wayne. In 1932, she was a member of the cast of Intermission, a play by Irving Kaye Davis in September 1932. The production opened in San Francisco, California and co-starred Madge Bellamy and Judith Voselli. Vaughn made her last onscreen appearance in the 1935 film The Live Wire opposite Richard Talmadge.